AVAREF Pillar
AVAREF’s core business is excellence in capacity building for clinical trials. To achieve this, the platform is structured around three interconnected supporting pillars that guide its actions and impact across Africa towards excellence in capacity building.
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Governance Structure
To ensure transparency, accountability, and regional representation, AVAREF operates under a formal governance structure aligned with the African Medicines Regulatory Harmonization (AMRH) initiative and the future African Medicines Agency (AMA)
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The AVAREF Secretariat and Key Functions
Hosted by the WHO Regional Office for Africa (WHO/AFRO) in Brazzaville, the AVAREF Secretariat coordinates all operations and supports the implementation of AVAREF’s strategic and technical activities. It serves as the operational hub of the network, ensuring alignment, communication, and capacity building across African countries. The Secretariat also mobilizes resources to support the member states and delivery of results.

Clinical Trial Reviews
Organizing joint and assisted clinical trial reviews, both virtually and in person

Training & Education
Coordinating training workshops, continuing education, and specialized webinars

Communication & Engagement
Managing communication, outreach, and partner engagement

Guidelines & Tools
Drafting and publishing guidelines, emergency frameworks, and technical tools

System Strengthening
Supports national regulatory and ethics ecosystems by conducting optimization missions, promoting best practices, and aligning country systems with other initiatives.

Expert Roster & Specialists
Maintaining the Roster of Experts, mobilizing technical specialists across clinical trial domains

